Type1 Diabetes has a Dual condition in children of age 7-12

There is research that shows that children under the age of seven have a different form of genotype as opposite to the condition prevalent with the children aged above 13. The destruction of the pancreas when the immune system of the body attacks the cells, type 1 diabetes take place in the body. A new study, at the University of Exeter, published in Diabetologia – shows that children under seven do not process insulin destroying the cells. New names suggested in the University of Exeter for new endotype are 1. Diabetes Endotype1 (T1DE2) 2. Type1 Diabetes Endotype 2 (T1DE2).


Prof Noel Morgan, from the university, says the significance of these two types, enabled them to understand the cause of illness and to protect the children from getting type1 diabetes. The children diagnosed under the age of 7-12 will fall in either of the two categories. The study emphasizes finding ways to reactivate dormant insulin-producing cells in older groups.

The Exeter team inferred by performing analyzing two bioresources that include the pancreatic biobank comprising of 130 samples, out of which the children diagnosed with type1 immediately died. The differences between the pancreas and blood of the people diagnosed with type1 are noted.


The therapies promise a lot of research in type1 diabetes as also immunotherapies that will slow disease progression. The era to immune attack behind type 1 diabetes is near.

Various conditions in child, adult, and adolescence are diagnosed to see a variation in types and conditions of type1. It is a bright chance ahead of the researchers to find a permanent cure to treat the children.