Gut condition are very normal and common between all humans. However, there are certain conditions that might be very rare and hard to cure or even understand. A diseases that falls under these circumstances is the Hirschsprung disease which is formed due to undeveloped nerves in the guts during birth. This causes many problems including the loss of the ability to contract and move bowels through the digestive system and other complications.
This disease is considered as a genetic disease as it is caused by a disorder in genes rather than any other malfunctions in the body. A study was conducted on the diseases which showed insights on other mental disorders that affects humans including complex diseases like schizophrenia and autism. The study conducted by Professors at NYU School of Medicine. Was published in the New England Journal of Medicine. The study was led by a PhD holder and the director of the Center for Human Genetics and Genomics, Dr. Aravinda Chakravarti.
Chakravarti commented on the results obtained saying, “We are finally understanding the genetics of Hirschsprung disease well enough to clarify the multiple key genes involved, the cellular mechanisms they alter, and the molecular targets against which drugs could be targeted to provide personalized treatment to patients. This condition results from three different classes of genetic changes, including previously underappreciated regions that regulate genes.”
This diseases affects almost one of every 5000 newly born babies and is genetically caused in almost 80% of all cases worldwide.