A new study has found that the muscles regulate their shape and quantity in defense from getting fractured. Bones change their shape in their lifetime. The bone regulation and resorption process is often a response to the force impelled by the pressing, pulling, and twisting of the skeleton due to routine movements.
The study of the shape of a bone says most of the bones are curved in nature, which describes that they work on engineering rules. As the saying goes, the straight trees are cut first, likewise, the straight bones are optimal in saving oneself. Unlike the curved bones that help in preventing fracture.
This study is carried by Royal Veterinary College (RVC) and Max Planck Institute of Colloids and Interfaces and University College London (UCL). This research used computational methods on 4D in vivo high-resolution micro-computed tomography for studying the shape changes on a bone, after it was artificially put under a known force. The quantification of 3D bone formation and checking of the resorption surfaces by conventional histology done. Their relation with local stress in bone tissue caused by physiological-force is studied.
Mr. Hajar Razi, Postdoctoral Researcher, Max Planck Institute of Colloids and Interfaces, detailed out, about bones nature, how they react to mechanical forces, and how an adaption of non-linear with local stimuli to achieve a larger bone curvature adjusted for load predictability.
As an inference, intelligent bone therapies that present the physiological forces save the curvature to resist fracture. Osteoporosis contributes to bending strength but current treatments do not focus on bones rather they have anti-resorptive/ pro-formative effects.